Depilus Cream: A Hair Removal Cream

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What is Depilus cream?

Depilus cream is used to treat hirsutism or to remove facial hairs. In other words, it is a hair removal cream. It contains a substance called eflornithine hydrochloride that slows or decreases the abnormal hair growth (hair removal cream). Depilus cream is applied to the affected area of the face or the other parts of the body. Depilus cream is used to remove excessive hair, especially in the patients with polycystic ovarian syndrome (PCO).

Depilus Cream 13.9% (Eflornithine hydrochloride)


What is the mechanism of action of Depilus cream?

It reduces follicular cell growth rate and slows down the hair growth. Eflornithine inhibits an enzyme named ornithine decarboxylase (ODC) present in the human skin and catalyses the biosynthesis of polyamines necessary for cell growth.

How to use Depilus cream: Check the video below

How Depilus is packed? Check video below.

What are indications of Depilus cream?

Depilus cream (Eflornithine HCL) is indicated in women with unwanted facial hair.

How to use Depilus cream?

To use Depilus cream, wash your mouth, dry it and then apply the cream gently two times a day. Wash your mouth after 4 hours. To get best results, massage a thin layer of the cream on chin, upper lip or other affected areas of face.

How long it takes to see improvement of hair removal?

It takes 4-8 weeks to see the improvement in hair removal. However, hair may regrow after the discontinuation of the treatment. It is not a depilatory preparation, but improves patient's appearance by reducing hair growth.

Can I use Depilus cream along with cosmetics, moisturizers and sunscreens?

Yes, Depilus cream can be used along with other cosmetics, moisturizers and sunscreens. You can apply Depilus cream first and wait till it dries before applying other skin products.

What are the side effects of Depilus cream?

Depilus or Eflornithine cream may cause side effects like acne, burning or tingling of the skin, stinging sensation, skin rash or swollen skin patches.

What are the precautions for Depilus cream usage?

Store it at room temperature (below 30 centigrade); keep it away from children; do not swallow it as it is only for external use; keep it in the container it comes packed in; avoid extreme heat, light or moisture; do not freeze it and avoid high doses.

Can children and the elderly people use Depilus cream?

For children below 12 years of age, the safety and effectiveness of Depilus (Eflornithine HCL) have not been established yet. However, in geriatrics, no apparent difference of safety and effectiveness has been observed.

Can topical eflornithine hydrochloride be used in addition to laser hair treatment?

Yes, studies have shown that topical use of eflornithine HCL enhances the hair removal and reduces inflammatory papules. Eflornithine HCL reduces follicular cell growth rate while laser hair treatment suspends hair growth by heating the hair and surrounding tissues.

What are the contraindications of Depilus cream use?

It should not be used during pregnancy and lactation. Also, it is contraindicated for those patients with known hypersensitivity to Depilus cream.

What is the price of Depilus cream?

The price of Depilus cream (15 grams laminated flexible tube) is Rs. 780.

In what brands Eflornithine is available?

Depilus creamVaniqa cream

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Keywords: Depilus cream, Eflornithine cream, ornithine decarboxylase, hair removal cream, side effects of Depilus cream, Remove facial hair, How to use Depilus cream, Contraindications, Vaniqa cream, Epila, Eflogen

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